PATHWAYS FROM ADVERSE CHILDHOOD EXPERIENCES TO DRUG ABUSE: STRESS AS A MEDIATOR AND EMOTIONAL INTEREST AS A MODERATOR

Abstract

Multiple factors can influence the relationship between adverse childhood experiences (ACEs) and drug abuse. This study examined whether stress mediates the association between ACEs and substance use—specifically co-use, nicotine use, and cannabis use—and whether this mediation effect varies as a function of emotional interest. A total of 249 participants completed measures assessing demographics, ACEs, stress, and drug misuse, along with a delay discounting task. Data were collected using the snowball sampling technique. Analyses were conducted using Hayes’ PROCESS macro (Version 3.4, Model 15) with moderated mediation and Pearson correlations. The results revealed a significant association between ACEs and drug misuse, with stress serving as a mediator in this relationship. Furthermore, emotional interest was found to moderate the link between ACEs and stress. These findings highlight the complex interplay between early adverse experiences, emotional regulation, and substance use behaviors.